General Industry
Evaluation performed by: Licensed physician (familiar with App A health effects, App F sampling protocol, and App D questionnaire; employer-selected, multiple-physician review available to employee)
Initial exam within 30 days of initial assignment (or 90 days after the standard's effective date, whichever is later); not required if an adequate exam was performed in the preceding 12 months
- Detailed medical + work history — emphasis on past, present, and anticipated cadmium exposure; renal, cardiovascular, respiratory, hematopoietic, reproductive, and musculo-skeletal dysfunction; current medications with nephrotoxic side-effects; smoking history and status
- Biological monitoring: Cadmium in urine (CdU), standardized to g creatinine (µg/g Cr)
- Biological monitoring: Beta-2-microglobulin in urine (β₂-M), standardized to µg/g Cr (pH specified)
- Biological monitoring: Cadmium in blood (CdB), standardized to liters whole blood (µg/lwb)
Interval-based while covered — NOT result-triggered
Schedule: Biological monitoring (CdU, β2-M, CdB) at least annually. Full medical examination within 1 year after the initial examination, then at least biennially thereafter (8 CCR 5207(l)(4)(A)).
- Biological monitoring at least annually: Cadmium in urine (CdU), standardized to g creatinine (µg/g Cr)
- Biological monitoring at least annually: Beta-2-microglobulin in urine (β₂-M), standardized to µg/g Cr (pH specified)
- Biological monitoring at least annually: Cadmium in blood (CdB), standardized to liters whole blood (µg/lwb)
- Biennial full exam — detailed medical + work history, or update thereof, with emphasis on past, present, and anticipated future exposure to cadmium; smoking history and current status; reproductive history; current use of medications with potential nephrotoxic side-effects; and any history of renal, cardiovascular, respiratory, hematopoietic, and/or musculo-skeletal system dysfunction — including App D questions 3-11 and 25-32 for employees who wear respirators
- Biennial full exam — complete physical examination with emphasis on blood pressure, the respiratory system, and the urinary system
- Biennial full exam — posterior-anterior chest X-ray (14×17-inch or equivalent standard film/digital; subsequent frequency per examining physician)
- Biennial full exam — pulmonary function tests: forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV₁)
- Biennial full exam — blood: blood urea nitrogen (BUN), complete blood count (CBC), serum creatinine
- Biennial full exam — urinalysis: albumin, glucose, and total and low-molecular-weight proteins
- Biennial full exam — prostate palpation (males over 40), or other at least as effective diagnostic test
- Any additional tests deemed appropriate by the examining physician
At termination of employment, for any employee to whom the employer was required to provide medical surveillance at any prior time under 8 CCR 5207(l)(1)(A) or (l)(7)
- Termination exam — detailed medical + work history, or update thereof, with emphasis on past, present, and anticipated future exposure to cadmium; smoking history and current status; reproductive history; current use of medications with potential nephrotoxic side-effects; and any history of renal, cardiovascular, respiratory, hematopoietic, and/or musculo-skeletal system dysfunction — including App D questions 3-11 and 25-32 for employees who wear respirators
- Termination exam — complete physical examination with emphasis on blood pressure, the respiratory system, and the urinary system
- Termination exam — posterior-anterior chest X-ray (14×17-inch or reasonably standard sized), expressly required as part of the termination examination
- Termination exam — pulmonary function tests: forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV₁)
- Termination exam — biological monitoring: cadmium in urine (CdU) standardized to g creatinine (µg/g Cr); beta-2-microglobulin in urine (β₂-M) standardized to µg/g Cr with pH specified; cadmium in blood (CdB) standardized to liters whole blood (µg/lwb)
- Termination exam — blood: blood urea nitrogen (BUN), complete blood count (CBC), serum creatinine
- Termination exam — urinalysis: albumin, glucose, and total and low-molecular-weight proteins
- Termination exam — prostate palpation (males over 40), or other at least as effective diagnostic test
- Termination exam — any additional tests deemed appropriate by the examining physician
- Required unless a qualifying examination meeting all of the above requirements was completed less than 6 months prior to the date of termination — and required even then where an elevated biological-monitoring result or an abnormal medical-examination finding independently calls for an examination under 8 CCR 5207(l)(3) or (l)(5)
- Not required for previously-exposed employees whose periodic medical surveillance has been discontinued under 8 CCR 5207(l)(4)(E)
As soon as possible following an acute cadmium exposure because of an emergency
- Emergency exam — detailed medical + work history, or update thereof, with emphasis on past, present, and anticipated future exposure to cadmium; smoking history and current status; reproductive history; current use of medications with potential nephrotoxic side-effects; and any history of renal, cardiovascular, respiratory, hematopoietic, and/or musculo-skeletal system dysfunction — including App D questions 3-11 and 25-32 for employees who wear respirators
- Emergency exam — complete physical examination with emphasis on blood pressure, the respiratory system, and the urinary system
- Emergency exam — posterior-anterior chest X-ray (14×17-inch or reasonably standard sized; subsequent frequency per examining physician)
- Emergency exam — pulmonary function tests: forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV₁)
- Emergency exam — biological monitoring: cadmium in urine (CdU) standardized to g creatinine (µg/g Cr); beta-2-microglobulin in urine (β₂-M) standardized to µg/g Cr with pH specified; cadmium in blood (CdB) standardized to liters whole blood (µg/lwb)
- Emergency exam — blood: blood urea nitrogen (BUN), complete blood count (CBC), serum creatinine
- Emergency exam — urinalysis: albumin, glucose, and total and low-molecular-weight proteins
- Emergency exam — prostate palpation (males over 40), or other at least as effective diagnostic test
- Emergency exam — any additional tests deemed appropriate by the examining physician
- Additional emphasis throughout on the respiratory system, other organ systems considered appropriate by the examining physician, and symptoms of acute overexposure as identified in App A subsections II2.(1)-(2) and IV
Abnormal results & exposure-event protocols
Abnormal Results & Exposure-Event Protocols
- Initial biological result CdU >3 µg/g Cr, OR β₂-M >300 µg/g Cr, OR CdB >5 µg/lwb Elevated biomonitoring response: Within 2 weeks reassess occupational exposure (work practices, respirator use, hygiene, engineering controls, smoking); within 30 days correct deficiencies; within 90 days provide a full medical examination. If not removed, continue semiannual biological monitoring and annual full exams until CdU ≤3, β₂-M ≤300, and CdB ≤5. Tests: Repeat biological monitoring: CdU, β₂-M, CdB, Full medical examination within 90 days
- Mandatory removal when both the initial and confirmatory biological results show CdU >7 µg/g Cr, OR CdB >10 µg/lwb, OR β₂-M >750 µg/g Cr — AND concurrently CdU >3 or CdB >5. Pre-1999 absolute triggers (CdU >15, CdB >15, or β₂-M >1,500 with concurrent CdU >3 or CdB >5) also apply. Medical Removal Protection — post-1999 trigger levels (in force): Remove the employee from work where exposure is at/above the action level (or above the PEL if the basis is inability to wear a respirator). During removal, provide follow-up biological monitoring at least every 3 months and follow-up medical examinations at least every 6 months. Maintain MRP wage/benefit protection up to 18 months. Tests: Quarterly biological monitoring during removal: CdU, β₂-M, CdB, Semiannual follow-up medical examination during removal
- Employee removed under the MRP trigger levels Return to work / 18-month final determination: Return permitted only when CdU falls to ≤3 µg/g Cr AND CdB ≤5 µg/lwb AND β₂-M ≤300 µg/g Cr (physician may override with special-circumstances finding of no increased risk). After 18 months of unresolved removal, a final medical determination exam decides return-to-former-status vs. permanent removal. Tests: Confirmatory biological monitoring (CdU, CdB, β₂-M) to establish return eligibility
Reporting Requirements
| Who performs the evaluation | Licensed physician (familiar with App A, App D, App F) |
|---|---|
| Reported to employer | Prompt written medical opinion containing: the physician's diagnosis; whether the employee has a detected condition increasing risk of material impairment from cadmium (including potential cadmium toxicity); results of biological/other tests assessing cadmium absorption; any recommended removal or limitation on duties/PPE; and a statement that the physician explained the results (including all biomonitoring and any condition needing further evaluation, plus diet/medication limits) to the employee. Physician instructed NOT to reveal findings/diagnoses unrelated to cadmium. |
| Reported to / for the employee | Employer furnishes a copy of the written opinion to the employee within 2 weeks of receipt; biological monitoring results plus an explanation sheet furnished within 2 weeks of receipt. |
| Time limits | Written opinion and biomonitoring explanation furnished to the employee within 2 weeks of employer receipt; employee must initiate second-physician review within 15 days of notice. |
| Second-opinion / multi-physician review | Multiple-physician review: employer must notify the employee of the right to a second opinion after each employer-arranged exam; employee designates a second physician; unresolved disagreements go to a jointly-designated third physician whose findings control. |
| Recordkeeping | Medical records retained for the duration of employment plus 30 years, in accordance with 8 CCR 5207(n)(3)(C) (citing section 3204 for access). Mirrors federal 1910.1027(n)(3)(iii). |
Medical Removal Protection
Mandatory removal at post-1999 confirmed CdU >7 / CdB >10 / β₂-M >750 (with concurrent CdU >3 or CdB >5); return at CdU ≤3 AND CdB ≤5 AND β₂-M ≤300; MRP wage/benefit protection up to 18 months; quarterly biomonitoring and semiannual exams during removal.
Construction
Evaluation performed by: Licensed physician (familiar with App A health effects, App F sampling protocol, and App D questionnaire; employer-selected, multiple-physician review available to employee)
Initial exam within 30 days of initial assignment (or 90 days after the standard's effective date, whichever is later); not required if an adequate exam was performed in the preceding 12 months
- Detailed medical + work history — emphasis on past, present, and anticipated cadmium exposure; renal, cardiovascular, respiratory, hematopoietic, reproductive, and musculo-skeletal dysfunction; current medications with nephrotoxic side-effects; smoking history and status
- Biological monitoring: Cadmium in urine (CdU), standardized to g creatinine (µg/g Cr)
- Biological monitoring: Beta-2-microglobulin in urine (β₂-M), standardized to µg/g Cr (pH specified)
- Biological monitoring: Cadmium in blood (CdB), standardized to liters whole blood (µg/lwb)
Interval-based while covered — NOT result-triggered
Schedule: Biological monitoring (CdU, β2-M, CdB) at least annually. Full medical examination within 1 year after the initial examination, then at least biennially thereafter (8 CCR 1532(l)(4)(A)).
- Biological monitoring at least annually: Cadmium in urine (CdU), standardized to g creatinine (µg/g Cr)
- Biological monitoring at least annually: Beta-2-microglobulin in urine (β₂-M), standardized to µg/g Cr (pH specified)
- Biological monitoring at least annually: Cadmium in blood (CdB), standardized to liters whole blood (µg/lwb)
- Biennial full exam — detailed medical + work history or update thereof, emphasis on past, present, and anticipated future cadmium exposure; smoking history and current status; reproductive history; current use of medications with potential nephrotoxic side-effects; any history of renal, cardiovascular, respiratory, hematopoietic, and/or musculo-skeletal system dysfunction (App D respirator questions 3-11 and 25-32 for respirator wearers)
- Biennial full exam — complete physical examination with emphasis on blood pressure, the respiratory system, and the urinary system
- Biennial full exam — posterior-anterior chest X-ray, 14×17-inch or a reasonably standard size (after the initial X-ray, frequency is determined by the examining physician)
- Biennial full exam — pulmonary function tests: forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV₁)
- Biennial full exam — blood: blood urea nitrogen (BUN), complete blood count (CBC), serum creatinine
- Biennial full exam — urinalysis: albumin, glucose, and total and low-molecular-weight proteins
- Biennial full exam — prostate palpation (males over 40), or other at least as effective diagnostic test
- Biennial full exam — any additional tests deemed appropriate by the examining physician
At termination of employment, for any employee to whom the employer was at any prior time required to provide medical surveillance under 8 CCR 1532(l)(1)(A) or (l)(7)
- Termination exam — detailed medical + work history or update thereof, emphasis on past, present, and anticipated future cadmium exposure; smoking history and current status; reproductive history; current use of medications with potential nephrotoxic side-effects; any history of renal, cardiovascular, respiratory, hematopoietic, and/or musculo-skeletal system dysfunction (App D respirator questions 3-11 and 25-32 for respirator wearers)
- Termination exam — complete physical examination with emphasis on blood pressure, the respiratory system, and the urinary system
- Termination exam — posterior-anterior chest X-ray where necessary, 14×17-inch or a reasonably standard size
- Termination exam — pulmonary function tests: forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV₁)
- Termination exam — biological monitoring: cadmium in urine (CdU) standardized to g creatinine (µg/g Cr); beta-2-microglobulin in urine (β₂-M) standardized to µg/g Cr (pH specified); cadmium in blood (CdB) standardized to liters whole blood (µg/lwb)
- Termination exam — blood: blood urea nitrogen (BUN), complete blood count (CBC), serum creatinine
- Termination exam — urinalysis: albumin, glucose, and total and low-molecular-weight proteins
- Termination exam — prostate palpation (males over 40), or other at least as effective diagnostic test
- Termination exam — any additional tests deemed appropriate by the examining physician
- Not required if the last examination meeting these requirements was less than 6 months prior to the date of termination, unless otherwise specified in 8 CCR 1532(l)(3) or (l)(5); also not required if the employer has discontinued all periodic medical surveillance under 8 CCR 1532(l)(4)(E)
As soon as possible following an acute cadmium exposure because of an emergency
- Post-exposure exam — detailed medical + work history or update thereof, emphasis on past, present, and anticipated future cadmium exposure; smoking history and current status; reproductive history; current use of medications with potential nephrotoxic side-effects; any history of renal, cardiovascular, respiratory, hematopoietic, and/or musculo-skeletal system dysfunction (App D respirator questions 3-11 and 25-32 for respirator wearers)
- Post-exposure exam — complete physical examination with emphasis on blood pressure, the respiratory system, and the urinary system
- Post-exposure exam — posterior-anterior chest X-ray, 14×17-inch or a reasonably standard size (after the initial X-ray, frequency is determined by the examining physician)
- Post-exposure exam — pulmonary function tests: forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV₁)
- Post-exposure exam — biological monitoring: cadmium in urine (CdU) standardized to g creatinine (µg/g Cr); beta-2-microglobulin in urine (β₂-M) standardized to µg/g Cr (pH specified); cadmium in blood (CdB) standardized to liters whole blood (µg/lwb)
- Post-exposure exam — blood: blood urea nitrogen (BUN), complete blood count (CBC), serum creatinine
- Post-exposure exam — urinalysis: albumin, glucose, and total and low-molecular-weight proteins
- Post-exposure exam — prostate palpation (males over 40), or other at least as effective diagnostic test
- Post-exposure exam — any additional tests deemed appropriate by the examining physician
- Examination emphasis — the respiratory system, other organ systems considered appropriate by the examining physician, and symptoms of acute overexposure as identified in App A subsections II(B)(1)-(2) and IV
Abnormal results & exposure-event protocols
Abnormal Results & Exposure-Event Protocols
- Initial biological result CdU >3 µg/g Cr, OR β₂-M >300 µg/g Cr, OR CdB >5 µg/lwb Elevated biomonitoring response: Within 2 weeks reassess occupational exposure (work practices, respirator use, hygiene, engineering controls, smoking); within 30 days correct deficiencies; within 90 days provide a full medical examination. If not removed, continue semiannual biological monitoring and annual full exams until CdU ≤3, β₂-M ≤300, and CdB ≤5. Tests: Repeat biological monitoring: CdU, β₂-M, CdB, Full medical examination within 90 days
- Mandatory removal when both the initial and confirmatory biological results show CdU >7 µg/g Cr, OR CdB >10 µg/lwb, OR β₂-M >750 µg/g Cr — AND concurrently CdU >3 or CdB >5. Pre-1999 absolute triggers (CdU >15, CdB >15, or β₂-M >1,500 with concurrent CdU >3 or CdB >5) also apply. Medical Removal Protection — post-1999 trigger levels (in force): Remove the employee from work where exposure is at/above the action level (or above the PEL if the basis is inability to wear a respirator). During removal, provide follow-up biological monitoring at least every 3 months and follow-up medical examinations at least every 6 months. Maintain MRP wage/benefit protection up to 18 months. Tests: Quarterly biological monitoring during removal: CdU, β₂-M, CdB, Semiannual follow-up medical examination during removal
- Employee removed under the MRP trigger levels Return to work / 18-month final determination: Return permitted only when CdU falls to ≤3 µg/g Cr AND CdB ≤5 µg/lwb AND β₂-M ≤300 µg/g Cr (physician may override with special-circumstances finding of no increased risk). After 18 months of unresolved removal, a final medical determination exam decides return-to-former-status vs. permanent removal. Tests: Confirmatory biological monitoring (CdU, CdB, β₂-M) to establish return eligibility
Reporting Requirements
| Who performs the evaluation | Licensed physician (familiar with App A, App D, App F) |
|---|---|
| Reported to employer | Prompt written medical opinion containing: the physician's diagnosis; whether the employee has a detected condition increasing risk of material impairment from cadmium (including potential cadmium toxicity); results of biological/other tests assessing cadmium absorption; any recommended removal or limitation on duties/PPE; and a statement that the physician explained the results (including all biomonitoring and any condition needing further evaluation, plus diet/medication limits) to the employee. Physician instructed NOT to reveal findings/diagnoses unrelated to cadmium. |
| Reported to / for the employee | Employer furnishes a copy of the written opinion to the employee within 2 weeks of receipt; biological monitoring results plus an explanation sheet furnished within 2 weeks of receipt. |
| Time limits | Written opinion and biomonitoring explanation furnished to the employee within 2 weeks of employer receipt; employee must initiate second-physician review within 15 days of notice. |
| Second-opinion / multi-physician review | Multiple-physician review: employer must notify the employee of the right to a second opinion after each employer-arranged exam; employee designates a second physician; unresolved disagreements go to a jointly-designated third physician whose findings control. |
| Recordkeeping | Medical records retained for the duration of employment plus 30 years (8 CCR 3204). |
Medical Removal Protection
Mandatory removal at post-1999 confirmed CdU >7 / CdB >10 / β₂-M >750 (with concurrent CdU >3 or CdB >5); return at CdU ≤3 AND CdB ≤5 AND β₂-M ≤300; MRP wage/benefit protection up to 18 months; quarterly biomonitoring and semiannual exams during removal.